Investigators Say DNA From Glove Linked to Guthrie Case Did Not Correspond to Any Known Records

Federal investigators have released a significant update in the search for Nancy Guthrie, revealing that DNA recovered from a glove found near her Arizona home has produced no matches in national databases.

Authorities confirmed Tuesday that genetic material collected from the glove—discovered roughly two miles from Guthrie’s Tucson residence—did not correspond to any profiles in the FBI’s Combined DNA Index System (CODIS). Pima County Sheriff Chris Nanos explained, “We’re hopeful we’re getting closer, but the latest results show that the DNA submitted from the glove came back with no hits in CODIS.”

Additional DNA samples recovered inside Guthrie’s home also failed to match any existing records. Investigators have clarified that the genetic material found on the glove differs from that found within the residence.

The black glove is considered potentially crucial evidence, as it resembles one worn by a masked individual captured on surveillance footage outside Guthrie’s home prior to her abduction. While more than a dozen gloves were collected during the initial search, most were determined to have been dropped inadvertently by search teams. The FBI has not confirmed whether other gloves remain under review.

Typically, CODIS results are available within 24 hours of submission. The system cross-references DNA evidence from crime scenes against profiles of individuals convicted of violent crimes—or, in some states, any felony.

Despite extensive efforts, investigators have yet to identify suspects or persons of interest in Guthrie’s disappearance. The mother of “Today” show host Savannah Guthrie was last seen on the evening of January 31. Sheriff Nanos noted that authorities are currently managing between 40,000 and 50,000 leads as the investigation continues.